To investigating the effects of various concentrations of nitrogen (180, 230, 280 and 330 mg L^-1) and potting media composition (peat moss:perlite or cocopeat:perlite as 2:1 V/V) on some growth traits of Euphorbia pulcherrima,  a factorial experiment was conducted based on a completely randomized design with 8 treatments and 3 replications. The results showed that the highest height, plant canopy diameter and protein content eamed by using of were observed in plants grown at the concentration of 230 mg L^-1 N in cocopeat and perlite media. The concentration of 230 mg L^-1 N increased the bract and leaf area in comparison with the other treatments. The concentration of 280 mg L^-1 of nitrogen with cocopeat and perlite media caused the maximum amount of the Mg content in plant leaves tissue. Using of peat mass and perlite and 330 mg L^-1 of nitrogen resulted in the highest bract anthocyanin and potassium content. Generally, the results of the study showed that the concentrations of 230 and 280 mg L^-1 nitrogen and the combination of cocopeat and perlite as a media improved the growth indices and qualitative characteristics of Poinsettia.