In order to study the effect of aqueous extract and essential oil of six plant species belong to Lamiaceae and Apiaceae family on controlling some important pests and qualitative characteristics of melon fruit (Khatuni cultivar), an experiment was conducted at the Boshruyeh region (Geographical coordinates: longitude 57°27' E and latitude 33°53' N) during the cropping season 2016-17.  The experimental design was a randomized complete block design with 20 treatments and 3 replications. The treatments consist of (chemical control, No-applied aqueous extract and essential oil, aqueous extract of Asafetida-Ferula 8, 10 and 12%, essence of Rosemary, Lavender, Peppermint, Fennel and Cumin 2, 2.5 and 3%. The results showed that the effect of treatment on White flies, Alfalfa weevils. Mite and healthy and damaged fruits was significant. Comparison of mean values revealed ineffectiveness of aqueous extract and essential oil on the population of whitefly, but the effects of 12% aqueous extract of Asafetida-Ferula on Alfalfa weevils population, and 3% concentrations of rosemary and black cumin on the mite population were significant. But, these treatments had not significant different with chemical control. The highest number of healthy fruits and the lowest number of damaged fruits were observed in treatments with 12% aqueous extract of Asafietida-Ferula and 3% essential oil of black cumin and peppermint.