In this experiment one determinate line and one indeterminate F₁ hybrid tomato (Moneymaker × San Marzano) were grafted on two potato cultivars (Agria and Satina) as root stock. Experiment was conducted as factorial based on CRD design with four replications. Some traits related to growth, physiology, yield and fruit quality of tomato including the foliage fresh and dry weight, plant height, chlorophyll index, fruit weight, total soluble solids and titratable acidity were assessed. The highest fruit yield (0.29 kg per plant) was obtained in graft combination of indeterminate tomato on Agria rootstocks this treatment also showed the best growth parameters and fruit quality. When indeterminate growth tomato was grafted on potato rootstocks, none of them (cv. Agria and Satina) produced tubers, while when these potatoes were grafted by determinate growth tomato both of them produced tubers as well as tomato fruits. Results indicated the existence of scion-rootstock interaction at least for potato tuberization and it seems producing two satisfactory crops from one grafted plant need more search for finding suitable tomato scion and potato rootstocks.